USE UNDER THE SUPERVISION OF A DOCTOR. Your baby's health depends on carefully following these easy directions. Proper hygiene, handling, and storage are important when preparing infant formula. Failure to follow these directions could result in severe harm. Powdered infant formulas are not sterile. Although Similac NeoSure is formulated for premature infants, powdered infant formulas should only be fed to premature infants or infants who might have immune problems as directed and supervised by your baby's doctor. Consult your baby's doctor about the formula appropriate for your baby; the need to use cooled, boiled water for mixing; and the need to boil utensils, bottles and nipples in water before use. Wash your hands, surfaces and utensils. Pour desired amount of water into bottle (see chart below). Add powder; return dry scoop to can. Cap bottle; shake well; attach nipple. Once feeding begins, use within 1 hour or discard. Use enclosed scoop to measure powder. 2-fl-oz bottle: 2 fl oz water, 1 unpacked level scoop (9.6 g) powder. 4-fl-oz bottle: 4 fl oz water, 2 unpacked level scoops powder. 6-fl-oz bottle: 6 fl oz water, 3 unpacked level scoops powder. 8-fl-oz bottle: 8 fl oz water, 4 unpacked level scoops powder. To make a larger amount of formula using a standard measuring cup, add 1 unpacked, level cup (NOT the enclosed scoop) of powder (100 g) to 21 fl oz of water. Yields approximately 24 fl oz of formula. To maintain freshness, pour prepared formula into individual feeding bottles; cap and store in refrigerator. Prepared formula should not be left unrefrigerated. Storage: Immediately store prepared individual feeding bottles in refrigerator at 35-40 degrees F (2-4 degrees C) and use within 24 hours. Store unopened cans at room temperature; avoid extreme temperatures. Cover opened can and store in a cool dry area (not in refrigerator). Use opened can contents within 1 month.